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Friends of Esquipulas is a non-profit organization in Louisville, Kentucky which is organized to support the Sister Parish Relationship between the communities of St. William in Louisville and Our Lord of Esquipulas in Nicaragua, as well as the work of the Developing Communities organization in Esquipulas.  

The parish of Our Lord of Esquipulas is located in the Matagalpa Diocese of Nicaragua, in the northern highlands. The parish itself has over 33 separate communities within a radius of 20 miles from the urban center of Esquipulas; 23 of these communities have chapels as shown in the map below.